{"id":3838,"date":"2025-07-29T14:59:27","date_gmt":"2025-07-29T06:59:27","guid":{"rendered":"https:\/\/webdept.fjuh.fju.edu.tw\/FjuhDep\/pharmacy\/?page_id=3838"},"modified":"2025-08-05T14:32:14","modified_gmt":"2025-08-05T06:32:14","slug":"%e6%9c%9f%e5%88%8a%e5%b0%8e%e8%ae%80","status":"publish","type":"page","link":"https:\/\/webdept.fjuh.fju.edu.tw\/FjuhDep\/pharmacy\/%e6%9c%9f%e5%88%8a%e5%b0%8e%e8%ae%80\/","title":{"rendered":"\u671f\u520a\u5c0e\u8b80"},"content":{"rendered":"\t\t
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\u6162\u6027\u9f3b\u7ac7\u708e\u7684\u9996\u9078\uff1f\u4f55\u6642\u61c9\u8a72\u6539\u7528\u5176\u4ed6\u9078\u64c7\u5462\uff1f<\/span><\/span><\/span><\/u><\/p><\/u><\/a><\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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Gabapentinoid <\/span>\u53ef\u4ee5\u653e\u5fc3\u4f7f\u7528\u55ce\uff1f\uff0d2024<\/span>\u5e74\u70ba\u6b62\u7684\u8af8\u591a\u8b66\u8a0a\u4ecd\u9808\u7559\u610f<\/span><\/u><\/p><\/u><\/a><\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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\u9810\u9632<\/span> CKD <\/span>\u6700\u65b0\u5229\u5668\uff0d<\/span>Kerendia <\/span>\u5408\u4f75<\/span> Jardiance <\/span>\u7684\u6700\u65b0\u5be6\u8b49\uff1a<\/span>CONFIDENCE trial<\/span><\/span><\/u><\/p><\/u><\/a><\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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\u6162\u6027\u9f3b\u7ac7\u708e\u7684\u9996\u9078\uff1f\u4f55\u6642\u61c9\u8a72\u6539\u7528\u5176\u4ed6\u9078\u64c7\u5462\uff1f<\/h1>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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\u5728 Oral Agents or Nasal Sprays for Allergic Rhinitis \u9019\u7bc7\u671f\u520a\u5c0e\u8b80\u4e2d\u544a\u8a34\u4e86\u6211\u5011\uff1a<\/span><\/h4>

1.\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <\/span><\/span>\u7121\u8ad6\u662f\u5c0d\u6bd4\u53e3\u670d\u6297\u7d44\u7e54\u80fa\u6216\u767d\u4e09\u70ef\u985e\u62ee\u6297\u5291\uff0c\u9f3b\u7528\u985e\u56fa\u9187\u90fd\u66f4\u986f\u8457\u6539\u5584\u75c5\u60a3\u6162\u6027\u9f3b\u7ac7\u708e\u7684\u75c7\u72c0\u8207\u751f\u6d3b\u54c1\u8cea\uff0c\u540c\u7406\u9f3b\u7528\u6297\u7d44\u7e54\u80fa\u4e5f\u6bd4\u53e3\u670d\u7684\u66f4\u6709\u6548\u3002<\/span><\/p>

3.\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <\/span><\/span>\u96d6\u7136\u5df2\u6709\u4e86\u9996\u9078\u85e5\u7269\uff0c\u4f46\u6b21\u9078\u85e5\u7269\u4ecd\u6709\u503c\u5f97\u8003\u91cf\u4e4b\u8655\uff0c\u4f8b\u5982\u9f3b\u7528\u6297\u7d44\u7e54\u80fa\u76f8\u6bd4\u9f3b\u7528\u985e\u56fa\u9187\u66f4\u80fd\u5feb\u901f\u8d77\u6548\uff1b\u53e3\u670d\u85e5\u54c1\u66f4\u9069\u7528\u65bc\u4e0d\u559c\u6b61\u9f3b\u7528\u88fd\u5291\u7684\u75c5\u4eba\uff1b\u767d\u4e09\u70ef\u985e\u62ee\u6297\u5291\u9069\u5408\u7528\u65bc\u524d\u8ff0\u85e5\u54c1\u85e5\u6548\u4e0d\u4f73\u4e14\u5408\u4f75\u6c23\u5598\u7684\u75c5\u60a3\u3002<\/span><\/p>

4.\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <\/span><\/span>\u5c0d\u7279\u6b8a\u65cf\u7fa4\u4ecd\u9808\u6709\u7279\u6b8a\u8003\u91cf\uff0c\u6bd4\u5982\u5b69\u7ae5\u53ef\u4ee5\u5b89\u5168\u9078\u7528\u7684\u6297\u7d44\u7e54\u80fa\uff1f\u767d\u4e09\u70ef\u985e\u62ee\u6297\u5291\u5c0d\u5b69\u7ae5\u9700\u7279\u5225\u8003\u91cf\u7684\u526f\u4f5c\u7528\uff1f<\/span><\/p>

5.\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <\/span><\/span>\u6700\u5f8c\u662f\u00a0JAMA patient education page\u00a0<\/span>\u7684\u793a\u7bc4\u5716\u7247\uff0c\u9664\u85e5\u7269\u5916\u61c9\u6ce8\u610f\u7684\u885b\u6559\u7d30\u7bc0\uff1b\u5e0c\u671b\u9019\u7bc7\u6587\u7ae0\u80fd\u8b93\u85e5\u5e2b\u7406\u89e3\u4f7f\u7528\u9f3b\u5674\u5291\u578b\u7684\u597d\u8655\u8207\u91cd\u8981\u6027\uff0c\u4ee5\u53ca\u63a1\u7528\u5176\u4ed6\u85e5\u7269\u7684\u8003\u91cf\u9ede\u3002<\/span>\u00a0<\/span><\/span><\/h4>

\u8cc7\u6599\u4f86\u6e90\uff1aNEJM journal watch-Oral Agents or Nasal Sprays for Allergic Rhinitis?<\/u><\/a><\/span>\u00a0<\/span><\/h4>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Gabapentinoid \u53ef\u4ee5\u653e\u5fc3\u4f7f\u7528\u55ce\uff1f\uff0d2024\u5e74\u70ba\u6b62\u7684\u8af8\u591a\u8b66\u8a0a\u4ecd\u9808\u7559\u610f<\/h1>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
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Neurotin <\/span>\u548c Lyrica <\/span>\u662f\u975e\u5e38\u5be6\u7528\u7684\u85e5\u54c1\uff0c\u56e0\u70ba\u6a5f\u8f49\u4e0d\u540c\u53ef\u8207\u5176\u4ed6\u6b62\u75db\u85e5\u4e26\u7528\uff1a<\/span><\/p>

\u5291\u91cf\u7bc4\u570d\u5ee3\u6cdb<\/b><\/span><\/u>\uff1aLyrica 150mg<\/span>\uff1a4 cap\/day<\/span>\uff0cNeurotin 300mg<\/span>\uff1a12 cap\/day<\/span>\u3002<\/span><\/p>

\u9069\u61c9\u75c7\u5ee3\u6cdb<\/b><\/span><\/u>\uff1a\u6db5\u84cb\u7672\u7647\u3001\u5404\u985e\u795e\u7d93\u75db\u3001\u7e96\u7dad\u808c\u75db\uff0c\u751a\u81f3\u7126\u616e\u75c7\u3002<\/span><\/p>

\u4e0d\u904e\uff0c\u5728\u88ab\u5ee3\u6cdb\u958b\u7acb\u7684\u60c5\u6cc1\u4e0b\uff0c\u66f4\u9700\u8b39\u614e\u7be9\u9078\u9069\u5408\u7684\u75c5\u4eba\u3002<\/span><\/p>

2024 <\/span>\u5e74\u591a\u7bc7\u6587\u7ae0\u56de\u9867\u4e86 gabapentinoid <\/span>\u985e\u85e5\u7269\u526f\u4f5c\u7528\u8207\u8b66\u8a0a\uff0c\u56e0\u6b64\u88ab\u9078\u5165 NEJM journal watch <\/span>\u7684 Year in Review<\/span>\u3002<\/span><\/p>

\u4ee5\u4e0b\u662f gabapentinoid <\/span>\u8fd1\u671f\u5099\u53d7\u95dc\u6ce8\u7684 4 <\/span>\u5927\u526f\u4f5c\u7528\uff1a<\/b><\/span><\/p>

1.\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <\/span><\/span>\u9ad6\u9aa8\u9aa8\u6298\uff1a<\/b><\/span><\/p>

\u5e74\u9577\u8005 (>50 <\/span>\u6b72) <\/span>\u56e0\u982d\u6688\u3001\u660f\u7761\u6613\u8dcc\u5012\uff0c\u589e\u52a0\u9ad6\u9aa8\u9aa8\u6298\u98a8\u96aa\uff0c2019 <\/span>\u5e74\u88ab\u5217\u5165 AGS Beers Criteria <\/span>\u6f5b\u5728\u4e0d\u9069\u7576\u7528\u85e5\u3002<\/span><\/p>

\u5e74\u9577\u4e14\u814e\u529f\u80fd\u4e0d\u4f73\u6216\u8eab\u9ad4\u865b\u5f31\uff0c\u98a8\u96aa\u5c07\u63d0\u9ad8 1.4 <\/span>\u8207 0.8 <\/span>\u500d (OR 2.4 & 1.8)<\/span>\u3002<\/span><\/p>

2.\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <\/span><\/span>\u547c\u5438\u56f0\u96e3<\/b><\/span>\uff1a<\/span><\/p>

2019 <\/span>\u5e74 US FDA <\/span>\u767c\u5e03 50 <\/span>\u4f8b gabapentinoid <\/span>\u5f15\u767c\u547c\u5438\u56f0\u96e3\u7684\u8b66\u8a0a\u3002<\/span><\/p>

\u7814\u7a76\u986f\u793a\uff0cCOPD <\/span>\u60a3\u8005\u4f7f\u7528 gabapentinoid <\/span>\u6703\u589e\u52a0\u56b4\u91cd\u6025\u6027\u767c\u4f5c\u7684\u98a8\u96aa (aHR 1.4) <\/span>\u53ca\u8f15\u4e2d\u5ea6\u6025\u6027\u767c\u4f5c (aHR 1.1)<\/span>\u3002<\/span><\/p>

\u4e0d\u50c5\u662f\u4e00\u822c\u4eba\u5bb9\u6613\u56e0\u6b64\u547c\u5438\u56f0\u96e3\uff0c\u672c\u5c31\u547c\u5438\u56f0\u96e3\u7684 COPD <\/span>\u60a3\u8005\u4e5f\u6703\u66f4\u52a0\u56b4\u91cd\u60e1\u5316\u3002<\/span><\/p>

3.\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <\/span><\/span>\u4e0b\u80a2\u6c34\u816b\u8207\u8655\u65b9\u7d1a\u806f<\/b><\/span>\uff1a<\/span><\/p>

\u4f7f\u7528 CCB <\/span>\u6216 gabapentinoid <\/span>\u53ef\u80fd\u589e\u52a0\u4e0b\u80a2\u6c34\u816b\u98a8\u96aa (<\/span>\u5c0e\u81f4\u6c34\u5206\u6563\u81f3\u4e0b\u80a2\uff0c\u4f7f\u5f97\u8840\u7ba1\u5167\u5bb9\u7a4d\u6e1b\u5c11)<\/span>\u3002<\/span><\/p>

\u91ab\u5e2b\u958b\u65b9\u6642\u50be\u5411\u958b\u5229\u5c3f\u5291\u4f86\u89e3\u6c7a\u526f\u4f5c\u7528\uff0c\u800c\u5c0e\u81f4\u8655\u65b9\u7d1a\u806f (prescribing cascades)<\/span>\uff0c\u4f7f\u5f97\u4e0d\u5fc5\u8981\u7684\u85e5\u7269\u8ca0\u64d4\u66f4\u91cd\u3002<\/span><\/p>

\u4e0d\u4f46\u5b78\u7406\u4e0a\u96e3\u4ee5\u89e3\u6c7a (<\/span>\u4e26\u6c92\u6709\u8b93\u6c34\u5206\u56de\u5230\u8840\u7ba1\u5167)<\/span>\uff0c\u751a\u81f3\u53cd\u800c\u589e\u52a0\u6025\u8a3a\u6216\u4f4f\u9662\u98a8\u96aa (HR 1.21)<\/span>\u3002<\/span><\/p>

4.\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <\/span><\/span>\u610f\u8b58\u72c0\u614b\u6539\u8b8a<\/b><\/span>\uff1a<\/span><\/p>

Gabapentinoid <\/span>\u88ab\u5ee3\u6cdb\u7528\u65bc\u7126\u616e\u75c7\uff0c\u4f46\u81ea\u6b98\u884c\u70ba\u8207\u85e5\u7269\u904e\u91cf\u98a8\u96aa\u96a8\u4e4b\u63d0\u5347\uff0c\u5c24\u5176\u5728\u5e74\u8f15\u4eba\u8207\u9752\u5c11\u5e74\u4e2d\u66f4\u660e\u986f\u3002<\/span><\/p>

\u63d0\u9192\uff1a\u814e\u529f\u80fd\u4e0d\u826f\u8005\u9700\u5291\u91cf\u8abf\u6574\uff0c\u7136\u800c\u5373\u4f7f\u8abf\u6574\u5f8c\uff0c\u526f\u4f5c\u7528\u98a8\u96aa\u4ecd\u589e\u52a0\u3002<\/span><\/b><\/p>

\u8cc7\u6599\u4f86\u6e90\uff1aNEJM journal watch-Growing Evidence of Harms Associated with Gabapentinoid Drugs<\/u><\/a><\/span><\/b><\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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\n\t\t\t\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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\u9810\u9632 CKD \u6700\u65b0\u5229\u5668\uff0dKerendia \u5408\u4f75 Jardiance \u7684\u6700\u65b0\u5be6\u8b49\uff1aCONFIDENCE trial<\/h1>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
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\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\"\"\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\"\"\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\"\"\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
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\n\t\t\t\t\t\t\t\t\t

\u9664\u4e86\u6709\u76ca\u65bc\u5fc3\u8870\u7aed\u5916\uff0cMRA <\/span>\u8207 SGLT2i <\/span>\u5404\u81ea\u4e5f\u6709\u5be6\u8b49\u652f\u6301\u53ef\u5ef6\u7de9\u00a0CKD\u00a0<\/span>\u7684\u9032\u5c55\u3002\u7136\u800c\uff0c\u76ee\u524d\u9084\u672a\u6709\u4f5c\u70ba\u7d44\u5408\u4f7f\u7528\u65bc\u00a0CKD<\/span>\u7684\u81e8\u5e8a\u8a66\u9a57\u3002<\/span><\/p>

\u76f4\u5230\u4eca\u5e746<\/span>\u6708\uff0cNEJM\u00a0<\/span>\u4e0a\u767c\u8868\u4e86\u9019\u7bc7\u6587\u7ae0\u00a0(DOI:\u00a010.1056\/NEJMoa2410659<\/u><\/a>)<\/span>\uff0c\u5167\u5bb9\u8b1b\u8ff0\u4e86\u00a0Kerendia (finerenone) <\/span>\u8207Jardiance (empagliflozin) <\/span>\u5408\u4f75\u4f7f\u7528\u65bc\u540c\u6642\u60a3\u6709\u00a0CKD\u00a0<\/span>\u8207\u00a0DM\u00a0<\/span>\u7684\u75c5\u4eba\u53ef\u6709\u6548\u5ef6\u7de9\u814e\u529f\u80fd\u60e1\u5316\u4e26\u986f\u8457\u6539\u5584\u86cb\u767d\u5c3f\u3002\u7d50\u679c\u986f\u793a\u4f7f\u7528180<\/span>\u5929\u5f8c\uff0cKerendia <\/span>\u8207\u00a0Jardiance <\/span>\u5404\u81ea\u4f7f\u7528\u7686\u53ef\u964d\u4f4e\u00a0UACR\u00a0<\/span>\u7d0430%<\/span>\uff0c\u4f46\u5408\u4f75\u4f7f\u7528\u5247\u53ef\u964d\u4f4e\u7d04 50% (<\/span>\u6bd4\u503c 0.48<\/span>\uff1b95%\u00a0CI: 0.44<\/span>\u20130.54)<\/span>\u3002<\/span><\/p>

\u70ba\u4ec0\u9ebc\u6e1b\u5c11\u86cb\u767d\u5c3f\u9019\u9ebc\u91cd\u8981\u5462\uff1f<\/u><\/b><\/span><\/p>

1.\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<\/span><\/span>\u86cb\u767d\u5c3f\u6703\u76f4\u63a5\u50b7\u5bb3\u814e\u81df<\/span><\/b>\uff1a\u7576\u767d\u86cb\u767d\u88ab\u814e\u5c0f\u7ba1\u4e0a\u76ae\u7d30\u80de\u5438\u6536\uff0c\u6703\u5f15\u767c\u6eb6\u9176\u9ad4\u529f\u80fd\u969c\u7919\u3001\u6c27\u5316\u58d3\u529b\u53ca\u4fc3\u767c\u708e\u56e0\u5b50\u91cb\u653e
(<\/span>\u5982 NF-\u03baB<\/span>\u3001MCP-1<\/span>\u3001TGF-\u03b2)<\/span>\uff0c\u5c0e\u81f4\u5167\u76ae\u7d30\u80de\u529f\u80fd\u969c\u7919 (endothelial dysfunction)<\/span>\uff0c\u814e\u81df\u53d7\u640d\u3002<\/span><\/p>

2.\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<\/span><\/span>\u5f71\u97ff\u51dd\u8840\u7cfb\u7d71<\/span><\/b>\uff1a\u86cb\u767d\u5c3f\u6703\u5c0e\u81f4\u6297\u51dd\u8840\u86cb\u767d (<\/span>\u5982\u6297\u51dd\u8840\u9176 III<\/span>\u3001protein S) <\/span>\u6d41\u5931\uff0c\u4f7f\u8840\u6db2\u8655\u65bc\u9ad8\u51dd\u72c0\u614b (hypercoagulable state)<\/span>\uff0c\u5c0e\u81f4\u7d44\u7e54\u56e0\u5b50 (tissue
factor) <\/span>\u7684\u8868\u73fe\u91cf\u589e\u52a0\uff0c\u4fc3\u9032\u8840\u6813\u751f\u6210\u8207\u5fae\u8840\u7ba1\u708e\u75c7\u3002<\/span><\/p>

3.\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<\/span><\/span>\u4fc3\u9032\u6162\u6027\u767c\u708e\u8207\u52d5\u8108\u786c\u5316<\/span><\/b>\uff1a\u9577\u671f\u86cb\u767d\u5c3f\u6703\u9020\u6210\u6162\u6027\u767c\u708e\uff0c\u4fc3\u9032\u5167\u76ae\u7d30\u80de\u6d3b\u5316\u3001\u4f7f\u514d\u75ab\u7d30\u80de\u6d78\u6f64\u81f3\u8840\u7ba1\u58c1\uff0c\u5c0e\u81f4\u52d5\u8108\u7ca5\u6a23\u786c\u5316\u6591\u584a\u5f62\u6210\u8207\u60e1\u5316\u3002<\/span><\/p>

4.\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<\/span><\/span>\u52a0\u91cd\u5fc3\u8840\u7ba1\u98a8\u96aa<\/span><\/b>\uff1a\u6c27\u5316\u58d3\u529b\u3001\u767c\u708e\u3001\u9ad8\u51dd\u72c0\u614b\u8207\u5167\u76ae\u7d30\u80de\u529f\u80fd\u969c\u7919\u4e92\u76f8\u4f5c\u7528\uff0c\u6700\u7d42\u589e\u52a0\u5fc3\u8840\u7ba1\u4e8b\u4ef6\u767c\u751f\u7684\u6a5f\u7387\u3002<\/span><\/p>

\u5728 Change in albuminuria and subsequent risk of end-stage kidney\u00a0disease: an individual participant-level consortium meta-analysis of\u00a0observational studies (Coresh et al., 2019) <\/span>\u9019\u7bc7\u6587\u737b\u4e5f\u6307\u51fa\uff0c\u53ea\u8981\u57282<\/span>\u5e74\u5167\u8b93 UACR <\/span>\u964d\u4f4e\u81f3\u5c11 30%<\/span>\uff0c\u5c31\u80fd\u986f\u8457\u964d\u4f4e ESRD <\/span>\u7684\u98a8\u96aa (adjusted HR<\/span>\uff1a0.78<\/span>\uff1b95% CI: 0.66<\/span>\u20130.92<\/span>\uff0cESRD <\/span>\u98a8\u96aa\u964d\u4f4e\u4e8622%)<\/span>\u3002<\/span><\/p>

\u6b64\u5916\uff0cKDIGO staging system <\/span>\u7684\u7da0\u9ec3\u6a58\u7d05\u71c8\u8868\u683c\u4e5f\u986f\u793a\uff0cUACR <\/span>\u8d8a\u9ad8\uff0c\u672a\u4f86\u6d17\u814e\u6216\u91cd\u5927\u5fc3\u8840\u7ba1\u4e8b\u4ef6\u7684\u98a8\u96aa\u4e5f\u8d8a\u9ad8\u00a0(<\/span>\u7d05\u71c8 high risk <\/span>\u76f8\u7576\u65bc\u00a0low risk <\/span>\u7684150<\/span>\u500d)<\/span><\/span>\u3002<\/span><\/p>

\u4eca\u5e746<\/span>\u6708\u767c\u8868\u65bc EHJ <\/span>\u7684Cardiovascular Disease in Chronic Kidney Disease (<\/span>Marx-Sch<\/span>\u00fctt et al., 2025)\u00a0<\/span>\u66f4\u9032\u4e00\u6b65\u6307\u51fa\uff0c\u7576 UACR <\/span>\u5347\u9ad8 (300<\/span>\u20131000 mg\/g) <\/span>\uff0c\u5fc3\u8840\u7ba1\u6b7b\u4ea1\u7387\u4e5f\u6703\u96a8\u4e4b\u4e0a\u5347 (2.5<\/span>\u20133 <\/span>\u500d)<\/span>\u3002\u8a72\u6587\u4e5f\u7cfb\u7d71\u6027\u5f59\u6574\u4e86 CV\/CKD <\/span>\u5171\u75c5\u7684\u6cbb\u7642\u7b56\u7565\uff0c\u5f9e\u6a5f\u8f49\u5230\u6700\u65b0\u5be6\u8b49\u90fd\u6709\u8a73\u7d30\u8ad6\u8ff0\u3002<\/span><\/p>

\u76ee\u524d\u7528\u4f86\u9810\u4f30\u5341\u5e74\u5fc3\u8840\u7ba1\u4e8b\u4ef6\u7684\u5169\u500b\u6a21\u578b\uff1a\u6b50\u6d32\u7248 SCORE2 with CKD Add-on <\/span>\u8207\u7f8e\u570b\u7248 PREVENT tool<\/span>\uff0c\u7686\u53ef\u7d0d\u5165\u814e\u529f\u80fd\u76f8\u95dc\u56e0\u7d20\u8003\u91cf\u3002<\/span><\/p>

\u5728\u526f\u4f5c\u7528\u65b9\u9762\uff0cKerendia <\/span>\u8207 Jardiance <\/span>\u5408\u4f75\u4f7f\u7528\u6703\u7a0d\u5fae\u4f7f\u8840\u58d3\u4e0b\u964d\u3001\u8840\u9240\u4e0a\u5347\uff0c\u4f46\u4f4e\u8840\u58d3\u3001\u9ad8\u8840\u9240\u4e8b\u4ef6\u767c\u751f\u7387\u7121\u986f\u8457\u5dee\u7570\uff0c\u8840\u9240\u4e0a\u5347\u5e45\u5ea6\u4e5f\u4e0d\u6703\u6bd4\u55ae\u7368\u4f7f\u7528 Kerendia <\/span>\u9084\u9ad8\uff0c\u8db3\u4ee5\u8b49\u660e\u5176\u5b89\u5168\u6027\u3002<\/span><\/p>

\u9644\u8a3b\uff1aKerendia<\/span>\u76ee\u524d\u4e5f\u6709\u4f7f\u7528\u5728\u975e\u7cd6\u5c3f\u75c5\u60a3\u8005\u7684\u5ef6\u7de9\u814e\u529f\u80fd\u60e1\u5316\u3001\u5fc3\u814e\u529f\u80fd\u4e8b\u4ef6\u7d42\u9ede\u7684\u00a0trial\u00a0(FIND-CKD)\u00a0<\/span>\u9032\u884c\u4e2d\u3002<\/span><\/p>

\u8cc7\u6599\u4f86\u6e90\uff1aFinerenone with Empagliflozin in Chronic Kidney Disease and Type 2\u00a0Diabetes<\/u><\/a><\/span><\/span><\/strong><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"

\u6162\u6027\u9f3b\u7ac7\u708e\u7684\u9996\u9078\uff1f\u4f55\u6642\u61c9\u8a72\u6539\u7528\u5176\u4ed6\u9078\u64c7\u5462\uff1f Gabapentinoid \u53ef\u4ee5\u653e\u5fc3\u4f7f\u7528\u55ce\uff1f\uff0d2024\u5e74\u70ba\u6b62\u7684\u8af8\u591a […]<\/p>\n","protected":false},"author":68,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"ocean_post_layout":"full-width","ocean_both_sidebars_style":"","ocean_both_sidebars_content_width":0,"ocean_both_sidebars_sidebars_width":0,"ocean_sidebar":"","ocean_second_sidebar":"","ocean_disable_margins":"enable","ocean_add_body_class":"","ocean_shortcode_before_top_bar":"","ocean_shortcode_after_top_bar":"","ocean_shortcode_before_header":"","ocean_shortcode_after_header":"","ocean_has_shortcode":"","ocean_shortcode_after_title":"","ocean_shortcode_before_footer_widgets":"","ocean_shortcode_after_footer_widgets":"","ocean_shortcode_before_footer_bottom":"","ocean_shortcode_after_footer_bottom":"","ocean_display_top_bar":"default","ocean_display_header":"default","ocean_header_style":"","ocean_center_header_left_menu":"","ocean_custom_header_template":"","ocean_custom_logo":0,"ocean_custom_retina_logo":0,"ocean_custom_logo_max_width":0,"ocean_custom_logo_tablet_max_width":0,"ocean_custom_logo_mobile_max_width":0,"ocean_custom_logo_max_height":0,"ocean_custom_logo_tablet_max_height":0,"ocean_custom_logo_mobile_max_height":0,"ocean_header_custom_menu":"","ocean_menu_typo_font_family":"","ocean_menu_typo_font_subset":"","ocean_menu_typo_font_size":0,"ocean_menu_typo_font_size_tablet":0,"ocean_menu_typo_font_size_mobile":0,"ocean_menu_typo_font_size_unit":"px","ocean_menu_typo_font_weight":"","ocean_menu_typo_font_weight_tablet":"","ocean_menu_typo_font_weight_mobile":"","ocean_menu_typo_transform":"","ocean_menu_typo_transform_tablet":"","ocean_menu_typo_transform_mobile":"","ocean_menu_typo_line_height":0,"ocean_menu_typo_line_height_tablet":0,"ocean_menu_typo_line_height_mobile":0,"ocean_menu_typo_line_height_unit":"","ocean_menu_typo_spacing":0,"ocean_menu_typo_spacing_tablet":0,"ocean_menu_typo_spacing_mobile":0,"ocean_menu_typo_spacing_unit":"","ocean_menu_link_color":"","ocean_menu_link_color_hover":"","ocean_menu_link_color_active":"","ocean_menu_link_background":"","ocean_menu_link_hover_background":"","ocean_menu_link_active_background":"","ocean_menu_social_links_bg":"","ocean_menu_social_hover_links_bg":"","ocean_menu_social_links_color":"","ocean_menu_social_hover_links_color":"","ocean_disable_title":"default","ocean_disable_heading":"default","ocean_post_title":"","ocean_post_subheading":"","ocean_post_title_style":"","ocean_post_title_background_color":"","ocean_post_title_background":0,"ocean_post_title_bg_image_position":"","ocean_post_title_bg_image_attachment":"","ocean_post_title_bg_image_repeat":"","ocean_post_title_bg_image_size":"","ocean_post_title_height":0,"ocean_post_title_bg_overlay":0.5,"ocean_post_title_bg_overlay_color":"","ocean_disable_breadcrumbs":"default","ocean_breadcrumbs_color":"","ocean_breadcrumbs_separator_color":"","ocean_breadcrumbs_links_color":"","ocean_breadcrumbs_links_hover_color":"","ocean_display_footer_widgets":"default","ocean_display_footer_bottom":"default","ocean_custom_footer_template":"","footnotes":""},"class_list":["post-3838","page","type-page","status-publish","hentry","entry"],"_links":{"self":[{"href":"https:\/\/webdept.fjuh.fju.edu.tw\/FjuhDep\/pharmacy\/wp-json\/wp\/v2\/pages\/3838","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/webdept.fjuh.fju.edu.tw\/FjuhDep\/pharmacy\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/webdept.fjuh.fju.edu.tw\/FjuhDep\/pharmacy\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/webdept.fjuh.fju.edu.tw\/FjuhDep\/pharmacy\/wp-json\/wp\/v2\/users\/68"}],"replies":[{"embeddable":true,"href":"https:\/\/webdept.fjuh.fju.edu.tw\/FjuhDep\/pharmacy\/wp-json\/wp\/v2\/comments?post=3838"}],"version-history":[{"count":94,"href":"https:\/\/webdept.fjuh.fju.edu.tw\/FjuhDep\/pharmacy\/wp-json\/wp\/v2\/pages\/3838\/revisions"}],"predecessor-version":[{"id":3957,"href":"https:\/\/webdept.fjuh.fju.edu.tw\/FjuhDep\/pharmacy\/wp-json\/wp\/v2\/pages\/3838\/revisions\/3957"}],"wp:attachment":[{"href":"https:\/\/webdept.fjuh.fju.edu.tw\/FjuhDep\/pharmacy\/wp-json\/wp\/v2\/media?parent=3838"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}